Susan Jeffrey Authors and Disclosures
July 14, 2009 (Vienna, Austria) — Results of 2 new studies show that both the incidence and prevalence of dementia continue to rise in a linear fashion among the so-called “oldest old,” those in their 80s and 90s and even among centenarians.
The results, from the population-based Monzino 80-Plus Study in Italy and the 90+ Study in the United States, would appear to contradict fairly conclusively the previously held idea that conversion to dementia plateaus or even declines in this oldest-old population.
“The prevalence and incidence rates of dementia found in the Monzino 80-Plus study continue to rise also in very advanced ages,” Ugo Lucca, MD, from the Laboratory of Geriatric Neuropsychiatry at the Istituto di Ricerche Farmacologiche Mario Negri, in Milan, Italy. “Age remains the most important risk factor for dementia, and we need to further our understanding of its role if effective therapeutic and preventive strategies are to be developed.”
Claudia Kawas, MD, from the University of California, Irvine, showed a linear increase in dementia risk from 10% in the 90- to 95-year-olds to a “whopping” 41% for centenarians in the 90+ Study.
“I for one just spent about 2 decades of my career suggesting that the incidence rates of dementia go down after age 85,” she said. “This just goes to show that you really don’t know what you think you know.” Continue reading →