{"id":5556,"date":"2020-11-20T15:14:45","date_gmt":"2020-11-20T20:14:45","guid":{"rendered":"http:\/\/web.colby.edu\/cogblog\/?p=5556"},"modified":"2020-12-05T11:43:51","modified_gmt":"2020-12-05T16:43:51","slug":"cognitive-implications-of-a-journey-through-madness","status":"publish","type":"post","link":"https:\/\/web.colby.edu\/cogblog\/2020\/11\/20\/cognitive-implications-of-a-journey-through-madness\/","title":{"rendered":"Cognitive Implications of a &#8220;Journey Through Madness&#8221;"},"content":{"rendered":"<div id=\"attachment_5938\" style=\"width: 349px\" class=\"wp-caption alignright\"><a href=\"http:\/\/web.colby.edu\/cogblog\/files\/2020\/11\/Morpheus-1.jpg\"><img loading=\"lazy\" decoding=\"async\" aria-describedby=\"caption-attachment-5938\" class=\"wp-image-5938\" src=\"http:\/\/web.colby.edu\/cogblog\/files\/2020\/11\/Morpheus-1.jpg\" alt=\"\" width=\"339\" height=\"203\" \/><\/a><p id=\"caption-attachment-5938\" class=\"wp-caption-text\">Misconceptions about schizophrenia http:\/\/schizophreniasucks.blogspot.com\/2013\/07\/schizophrenia-memes.html<\/p><\/div>\n<p><span style=\"font-weight: 400\">Elyn Saks, an accomplished Professor of Law, Psychology, and Psychiatry and the Behavioral Sciences at University of Southern California Gould School of Law, has lived with schizophrenia for her entire life.\u00a0 In her memoir, \u201cThe Center Cannot Hold: My Journey Through Madness\u201d, Saks explains that the cognitive nature of her illness was a large factor in her decision to write a book. She speaks out about how she has struggled every single day living with this disorder, yet she was ultimately incredibly cognitively and professionally successful.\u00a0 Her disorder made it very\u00a0<\/span><span style=\"font-weight: 400\">difficult to hold attention in class or on school work when she was having a schizophrenic episode, and her diminished memory abilities made her work and relationships endure a different level of impairment.\u00a0<\/span><span style=\"font-weight: 400\">Elyn struggled with schizophrenia at a time when mental health was not at the forefront of societal concerns as it is today, and all of the symptoms she dealt with left her feeling alone and depressed, as making and keeping emotional connections with others was quite a troublesome task for her.\u00a0 So, here is an incredibly accomplished woman working at a prestigious institution who has endured a debilitating disorder that is stereotypically portrayed and misunderstood with a connotation of violent, dangerous, and potentially crazy individuals.\u00a0 The impressive work that Saks has done in sharing her story has contributed significantly to reducing the stigma of schizophrenia and has provided useful information in terms of the efficacy of various forms of treatment for the disorder, and you can click <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC2632545\/\">here<\/a> to learn more about the efficacy of psychological treatment in schizophrenia.\u00a0 My interest focused on how this crippling disorder affects individuals&#8217; cognitive processes, in particular considering the detrimental effects it has on both memory and attention.<\/span><\/p>\n<p><!--more--><\/p>\n<p><span style=\"font-weight: 400\">It is important to first give a quick overview of schizophrenia because in general, people&#8217;s beliefs about these individuals are quite often misconstrued from reality.\u00a0 Schizophrenia is a serious mental disorder in which people interpret reality abnormally as it affects their ability to think, feel, and behave clearly (Tripathi, Kar, &amp; Shukla, 2018) and impacts about 1.1% of the world\u2019s population.\u00a0 The disorder is characterized by thoughts or experiences that seem out of touch with reality, disorganized speech or behavior, and decreased participation in daily activities, as well as impaired concentration and memory. Additionally, a major issue related to the cognitive impairment of schizophrenics is that they often display poor learning and retention of verbal information.\u00a0\u00a0<a href=\"http:\/\/web.colby.edu\/cogblog\/2013\/04\/30\/memory-in-people-with-schizophrenia-what-is-impaired-what-is-preserved\/\">Memory impairment<\/a> is well documented in schizophrenia and various examinations of schizophrenic versus healthy individuals have suggested that there is a significant association between this disorder and the cognitive process of memory (Aleman, Hijman, de Haan, &amp; Kahn, 1999).\u00a0 But what is it about memory that makes it quite a problem for schizophrenic individuals?<\/span><\/p>\n<div id=\"attachment_5941\" style=\"width: 352px\" class=\"wp-caption alignleft\"><a href=\"http:\/\/web.colby.edu\/cogblog\/files\/2020\/11\/Long-Term-Memory.jpg\"><img loading=\"lazy\" decoding=\"async\" aria-describedby=\"caption-attachment-5941\" class=\"wp-image-5941\" src=\"http:\/\/web.colby.edu\/cogblog\/files\/2020\/11\/Long-Term-Memory-580x355.jpg\" alt=\"\" width=\"342\" height=\"209\" srcset=\"https:\/\/web.colby.edu\/cogblog\/files\/2020\/11\/Long-Term-Memory-580x355.jpg 580w, https:\/\/web.colby.edu\/cogblog\/files\/2020\/11\/Long-Term-Memory-768x470.jpg 768w, https:\/\/web.colby.edu\/cogblog\/files\/2020\/11\/Long-Term-Memory.jpg 850w\" sizes=\"(max-width: 342px) 100vw, 342px\" \/><\/a><p id=\"caption-attachment-5941\" class=\"wp-caption-text\">All of the components of our daily lives we attempt to store into our memory systems https:\/\/meteoreducation.com\/long-term-memory\/<\/p><\/div>\n<p><span style=\"font-weight: 400\">Simply put, memory can be considered as an organized filing system for information.\u00a0 Classified by duration, there are three different types of memories: sensory memories, short term memories, and long term memories.\u00a0 Sensory memories are the briefest form of memory, while short term memories are short term storage of a memory with minimal processing that is forgotten quickly, and long term memory is the long term storage of memory after elaborative processing has occurred. It is also critical to define the three main types of memories that can be stored in and retrieved from this long term memory, and these are episodic, semantic, and procedural memory.\u00a0 Episodic memory characterizes remembrance of specific episodes or experiences in one\u2019s life, semantic memory is for facts or knowledge, and procedural memory is for a skill or procedure.\u00a0 And the last term that will need defining is working memory, which is processing a unit of information that is the current form of attention.\u00a0 What has been found throughout schizophrenia research is that there is considerable impairment in both working memory and episodic memory for these individuals, with less issues discovered in terms of verbal short term memory and procedural memory <\/span><span style=\"font-weight: 400\">(<\/span><span style=\"font-weight: 400\">Kraguljac<\/span><span style=\"font-weight: 400\">, <\/span><span style=\"font-weight: 400\">Srivastava<\/span><span style=\"font-weight: 400\">, &amp; <\/span><span style=\"font-weight: 400\">Lahti<\/span><span style=\"font-weight: 400\">, 2013).\u00a0 So, why might schizophrenics have a problem with working memory and episodic memory? Well, it is quite difficult to focus on anything in order to process and encode it when experiencing hallucinations, delusions, and voices inside your head.\u00a0 Because working memory controls our consciousness and we need to process life instantly, it makes sense that schizophrenics might have trouble with this while experiencing an episode.\u00a0 Similarly, schizophrenics have difficulty remembering specific experiences in their lives which makes sense because they are not consistently mentally present.\u00a0 For example, when Elyn Saks experienced a schizophrenic episode while needing to study for an exam, she was unable to process the information she was learning due to impairment with her working memory from voices and distractions in her head.\u00a0 Her episodic memory for this event would be quite poor because there was so much going on in her mind that she would hardly remember studying for a seemingly unimportant exam at the time.\u00a0 For similar reasons, attention deficits are also highly common in schizophrenic individuals.<\/span><\/p>\n<div id=\"attachment_5600\" style=\"width: 408px\" class=\"wp-caption alignleft\"><a href=\"http:\/\/web.colby.edu\/cogblog\/files\/2020\/11\/Screen-Shot-2020-11-20-at-3.32.13-PM.png\"><img loading=\"lazy\" decoding=\"async\" aria-describedby=\"caption-attachment-5600\" class=\"wp-image-5600\" src=\"http:\/\/web.colby.edu\/cogblog\/files\/2020\/11\/Screen-Shot-2020-11-20-at-3.32.13-PM-580x325.png\" alt=\"\" width=\"398\" height=\"223\" srcset=\"https:\/\/web.colby.edu\/cogblog\/files\/2020\/11\/Screen-Shot-2020-11-20-at-3.32.13-PM-580x325.png 580w, https:\/\/web.colby.edu\/cogblog\/files\/2020\/11\/Screen-Shot-2020-11-20-at-3.32.13-PM-768x430.png 768w, https:\/\/web.colby.edu\/cogblog\/files\/2020\/11\/Screen-Shot-2020-11-20-at-3.32.13-PM-940x526.png 940w, https:\/\/web.colby.edu\/cogblog\/files\/2020\/11\/Screen-Shot-2020-11-20-at-3.32.13-PM.png 1132w\" sizes=\"(max-width: 398px) 100vw, 398px\" \/><\/a><p id=\"caption-attachment-5600\" class=\"wp-caption-text\">Brain activity https:\/\/www.firstpost.com\/tech\/science\/world-schizophrenia-day-understanding-the-mental-disorder-what-you-can-do-to-help-6697541.html<\/p><\/div>\n<p><span style=\"font-weight: 400\">Attention has been described as a filter of information, a spotlight focused on an aspect of the environment, and a glue that binds features of the environment together.\u00a0 Attention is an incredibly crucial aspect of our lives as it is the first step in the learning process because we must attend to something in order to process and encode it into our memories.\u00a0 An important distinction within the cognitive process of attention is that of automatic and controlled processes.\u00a0 Automatic processing is processing that occurs that we are not consciously aware of, is used for tasks that we how to do, and occurs quickly.\u00a0 Controlled processing, on the other hand, is processing that requires intentional effort and is slow, more time consuming, and used for new and complex tasks.\u00a0 It is interesting to look at how patients with schizophrenia respond to automatic and controlled processing tasks in order to understand how they might attend to various real life attentional situations.\u00a0 It has been found that schizophrenia patients have considerable issues with controlled processing tasks; however, their automatic processing stays intact (Crider, 1997).\u00a0 Because controlled processes are more conscious and arduous, schizophrenics experience limited cognitive capacity in these situations.<\/span><\/p>\n<p><span style=\"font-weight: 400\">Additionally, an important aspect of our attention and of these automatic and controlled processes is consideration of facilitation and inhibition and how these concepts might further affect schizophrenic patients.\u00a0 Facilitation is the tendency to perform tasks both faster and better, while inhibition is just the opposite as it is the tendency to perform tasks slower and more poorly.\u00a0 Relating to automatic and controlled processes, controlled processes can produce facilitation or inhibition, and automatic processes can produce facilitation or no effect.\u00a0 Consequently, schizophrenic patients tend to struggle more with inhibition and related functions, which are detrimental effects that largely impact those who struggle.\u00a0 Inhibition is arguably more important because it allows humans to resolve conflicts and distinguish between reality and fantasy, a critical skill that schizophrenics do not possess. This comes in the form of hallucinations and delusions in which, unlike healthy individuals who are able to inhibit this incoming information, schizophrenics see, hear, and believe things outside of reality because their brains cannot distinguish between reality and fantasy.<\/span><\/p>\n<div id=\"attachment_5943\" style=\"width: 332px\" class=\"wp-caption alignright\"><a href=\"http:\/\/web.colby.edu\/cogblog\/files\/2020\/11\/Depression-in-Schizophrenia-Management.jpg\"><img loading=\"lazy\" decoding=\"async\" aria-describedby=\"caption-attachment-5943\" class=\"wp-image-5943\" src=\"http:\/\/web.colby.edu\/cogblog\/files\/2020\/11\/Depression-in-Schizophrenia-Management.jpg\" alt=\"\" width=\"322\" height=\"214\" \/><\/a><p id=\"caption-attachment-5943\" class=\"wp-caption-text\">Depression&#8217;s prevalent role in schizophrenia https:\/\/psychscenehub.com\/psychinsights\/depression-in-schizophrenia-causes-importance-and-treatment\/<\/p><\/div>\n<p><span style=\"font-weight: 400\">Now, how do these cognitive impairments affect schizophrenic individuals? Most concretely, these people suffer from an impaired quality of life (Pascal de Raykeer et al., 2019).\u00a0 Due to impaired attention and memory cognitive processes, schizophrenics struggle in many aspects of life.\u00a0 And this struggle unfortunately often leads to a subsequent diagnosis of depression.\u00a0 About 40% of schizophrenic individuals are reported with depression (Upthegrove, Marwaha, &amp; Birchwood, 2017) which is an incredibly unfortunate statistic, but again not surprising after taking into account all of the mental difficulties these individuals endure.\u00a0 Interestingly, older schizophrenic adults suffer most from this impaired quality of life because the discussed cognitive impairments and depression more negatively impact this population range.\u00a0 Pascal de Raykeer and colleagues explain that for schizophrenic individuals aged 60 and older, schizophrenia ranks as high as third on a list of psychiatric disorders that result in a shortened life span.\u00a0 It is quite sad to think that these individuals endure the challenges of this disorder their whole lives and that instead of potentially getting better as they get older, their quality of life actually decreases as they get older.\u00a0 Obviously, this is not the case for all schizophrenics and treatment can be very helpful for many, however this trend has been researched and discussed consistently.<\/span><\/p>\n<p><span style=\"font-weight: 400\">Because people subconsciously rely on their cognitive processes, episodes that take away one&#8217;s ability to think clearly, attend to information in the environment, and remember experiences make for a very dark quality of life that in turn leads to depression and other complex psychological issues.\u00a0 Schizophrenia is an incredibly complicated and debilitating disorder, specifically for its impacts on daily life.\u00a0 Could you imagine being in a bad enough mental state that you don\u2019t remember to shower for a week, eat, or brush your teeth?\u00a0 Or attempting to write a paper and not being able to write as much as five words because voices inside your head are talking to you? I certainly could not, but I am optimistic that there are myriads of research examining how to effectively treat Schizophrenia and that there are people, such as Elyn Saks, who are willing to share their stories and explain to the world exactly how this disorder manifests itself.<\/span><\/p>\n<p>&nbsp;<\/p>\n<p style=\"text-align: center\"><span style=\"font-weight: 400\">References<\/span><\/p>\n<p><span style=\"font-weight: 400\">Aleman, A., Hijman, R., de Haan, E., &amp; Kahn, R. (1999). Memory impairment in schizophrenia: A meta-analysis.\u00a0 <\/span><i><span style=\"font-weight: 400\">The American Journal of Psychiatry, 156, <\/span><\/i><span style=\"font-weight: 400\">1358\u20131366. doi:10.1016\/s0920-9964(03)00060-4<\/span><\/p>\n<p><span style=\"font-weight: 400\">Crider, A. (1997). Perseveration in schizophrenia. <\/span><i><span style=\"font-weight: 400\">Schizophrenia Bulletin, 23(1)<\/span><\/i><span style=\"font-weight: 400\">, 63\u201374. doi:10.1093\/schbul\/23.1.63<\/span><\/p>\n<p><span style=\"font-weight: 400\">Kraguljac, N., Srivastava, A., &amp; Lahti, A. (2013). Memory deficits in schizophrenia: A selective review of functional magnetic resonance imaging (fMRI) studies. <\/span><i><span style=\"font-weight: 400\">Behavioral Sciences, 3(3)<\/span><\/i><span style=\"font-weight: 400\">, 330\u2013347. doi:10.3390\/bs3030330<\/span><\/p>\n<p><span style=\"font-weight: 400\">Pascal de Raykeer et al. (2019). Psychiatric symptoms and quality of life in older adults with schizophrenia spectrum disorder: results from a multicenter study. <\/span><i><span style=\"font-weight: 400\">European Archives of Psychiatry and Clinical Neuroscience<\/span><\/i><span style=\"font-weight: 400\">, 270(6), 673\u2013688. doi:10.1007\/s00406-019-01026-9\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400\">Saks, E. (2007). <\/span><i><span style=\"font-weight: 400\">The center cannot hold: My journey through madness. <\/span><\/i><span style=\"font-weight: 400\">New York: Hachette Books.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400\">Tripathi, A., Kar, S. K., &amp; Shukla, R. (2018). Cognitive deficits in schizophrenia: understanding the biological correlates and remediation strategies. <\/span><i><span style=\"font-weight: 400\">Clinical Psychopharmacology and Neuroscience, 16(1)<\/span><\/i><span style=\"font-weight: 400\">, 7\u201317. doi:10.9758\/cpn.2018.16.1.7<\/span><\/p>\n<p style=\"text-align: center\">\n","protected":false},"excerpt":{"rendered":"<p>Elyn Saks, an accomplished Professor of Law, Psychology, and Psychiatry and the Behavioral Sciences at University of Southern California Gould School of Law, has lived with schizophrenia for her entire life.\u00a0 In her memoir, \u201cThe Center Cannot Hold: My Journey Through Madness\u201d, Saks explains that the cognitive nature of her illness was a large factor [&hellip;]<\/p>\n","protected":false},"author":9127,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"ngg_post_thumbnail":0,"footnotes":""},"categories":[80216,80215],"tags":[370831],"_links":{"self":[{"href":"https:\/\/web.colby.edu\/cogblog\/wp-json\/wp\/v2\/posts\/5556"}],"collection":[{"href":"https:\/\/web.colby.edu\/cogblog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/web.colby.edu\/cogblog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/web.colby.edu\/cogblog\/wp-json\/wp\/v2\/users\/9127"}],"replies":[{"embeddable":true,"href":"https:\/\/web.colby.edu\/cogblog\/wp-json\/wp\/v2\/comments?post=5556"}],"version-history":[{"count":13,"href":"https:\/\/web.colby.edu\/cogblog\/wp-json\/wp\/v2\/posts\/5556\/revisions"}],"predecessor-version":[{"id":6157,"href":"https:\/\/web.colby.edu\/cogblog\/wp-json\/wp\/v2\/posts\/5556\/revisions\/6157"}],"wp:attachment":[{"href":"https:\/\/web.colby.edu\/cogblog\/wp-json\/wp\/v2\/media?parent=5556"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/web.colby.edu\/cogblog\/wp-json\/wp\/v2\/categories?post=5556"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/web.colby.edu\/cogblog\/wp-json\/wp\/v2\/tags?post=5556"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}